100%  Phyllomedusa bicolor

The skin secretions from the the Giant Monkey Tree Frog or Phyllomedusa bicolor, that inhabits certain parts of the Brazilian rainforest, is a traditional remedy in the Amazon used as a medicine by indigenous tribes such as the Katukina, Yawanawa, Cashinahua and Matses. The purpose of applying this waxy natural poison is to induce a deep cleansing of the body and the soul, to support hunters in the jungle, to give strength, and to promote healing of other diseases. The frog is treated with respect and never harmed because, according to Amazonian beliefs, harming it would anger the animal spirit and thus fail to produce healing. After the extraction, the frog is released back into the forest.

Following the on-going researchers around the world, Kambo is one of the strongest, anti-inflammatory, antibiotic, antimicrobial and anesthetic substances on the planet. It is being studied for its effects on various types of cancer and for use in anti-biotic resistant strains of bacteria. Kambo has a detoxifying effect on the internal organs, including the liver (usually one vomits up bile) and the intestines (through evacuations) as well as the entire digestive system. 

An Italian scientist, Vittorio Erspamer, of the University of Rome was the first to analyze Kambo in the laboratory. Twice nominated for a nobel prize and responsible for first discovering the neurotransmitter Serotonin. The peptides discovered by Erspamer in Kambo trigger a variety of beneficial chemical reactions in the human body. Kambo has the ability, unlike many other natural and pharmaceutical substances, to cross the blood-brain barrier, enabling it to reach deep into the body and bring support to otherwise difficult to treat areas.  Human cells open up to the beneficial properties of this ancestral remedy unlike many substances that are filtered and eliminated by the body’s highly intelligent defense system.

Dermaseptins (DRSs) are a family of peptides that are part of the skin secretions of Kambo. In 1991, the first DRS was identified and characterized as a peptide rich in basic amino acids. By now, there are more than a hundred DRSs classified as antimicrobial peptides (AMPs), since they show effectivity against some bacteria, parasites, yeasts, protozoa, viruses and display boosting effects in the immune system.

Thus far, researchers have discovered nine peptides, some of which are bio-active – meaning that they perform specific functions in the body. These peptides perform hormone-like tasks while others provide support to vital cellular processes and have a potent effect on the gastrointestinal muscles, gastric and pancreatic secretions, blood circulation, and on the stimulation of the adrenal cortex and pituitary gland. Many peptides have since been isolated from the Kambo secretion and have been synthesized. As a testament to their medicinal properties, there are over 70 Kambo patents lodged, mainly in the USA. *You can download more articles regarding the scientific studies at the end of the article.

Kambo also contains certain neuropeptides, protein-like molecules used by the neurons to communicate with each other which are involved in a wide range of brain functions. Some of the major peptides identified in the Kambo secretion are Phyllomedusin, Caerulein, Sauvagine, Dermorphin, Deltorphin, Adenoregulin, Bombesins, Dermaseptin B2, responsable of the overwhelming benefits of this pure organic remedy from nature. 



· Analgesic effects 4000 times stronger than morphine and 40 times stronger than endogenic b-endorphines.

· Boosts metabolism.
· Depression, anxiety and stress significantly decrease.
· Used in alleviation of migraines and brain diseases Alzheimer’s and Parkinson’s.
· Capacity to destroy various types of microbes and viruses.
· Anti-inflammatory properties.
· Strongly affects intestines, bowels and contributes to deep purging of toxins.
· Stimulate the adrenal cortex and the pituitary gland contributing to heightened sensory perception and increased stamina.
· Improves blood circulation and vascular sufficiency.
· Fights organ diseases, skin and eyes issues.
· Enhance endurance, increase physical strength, and in general, rises the capacity to manage physical pain and stress.
· Effective at acquired immune deficiency syndrome (HIV/AIDS)
· Used to support the treatment and prevention of cancer, hepatitis, fertility problems, and fibromialgia.


Native tribes have worked safely with Kambo for generations is very safe when taken correctly. It is only now that Kambo has been used outside of the tribal setting and by non-native people that some problems have occurred. Please note that Kambo is not for you if you meet/have any of the following conditions:

Stroke • Heart bypass surgery • Enlarged heart • Implanted cardioverter defibrillators • Pericardial effusion • Congestive heart disease • Excess fluid in the heart sack • Heart valve replacement surgery • Organ transplant • Taking medicine for blood clots • Pregnancy • Serious mental health problem (excluding PTSD, depression and anxiety) • Epilepsy • Bipolar disorder • Within a month of chemotherapy or radiotherapy • Taking Diuretics • Taking immunosuppressants for an organ transplant • Addison’s disease • Recovering from a major surgical procedure • Person is water fasting for more than 12 hours • Person received an enema within 3 days prior • The person is being cajoled into doing Kambo by another person (including a family member) • The person lacks the mental capacity to make the decision to take Kambo • The person is desperate for a solution to a life-threatening problem • The person has consumed large amounts of water prior to arriving for Kambo • Person has eaten within 8 hours of receiving Kambo. • The person has not consumed 1-1.5L of water immediately prior to receiving Kambo.

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